On December 3rd, the artemisinin drug developed by our pharmacist Tu Yu and her team is still the world's leading antimalarial drug, which has saved millions of lives. A breakthrough study published online in the US Cell on December 1st showed that the drug may also save hundreds of millions of people with diabetes. Scientists from institutions such as the CeMM Center for Molecular Medicine in the Austrian Academy of Sciences, using a specially designed, fully automated analysis, have examined the effects of a large number of approved drugs on artificially cultured alpha cells. As a result, it was surprisingly found that artemisinin can cause the glucagon-producing alpha cells to "transform" to produce beta cells of insulin. The study's correspondent Stefan Kubicek said that the absolute and relative lack of insulin and the over-activation of the glucagon signaling pathway are the two leading causes of diabetes. Replacing damaged beta cells in patients with new cells that secrete insulin is expected to be a simple strategy for curing type 1 diabetes. Over the years, in order to achieve this, researchers around the world have tried a variety of methods using stem cells or mature cells. It is worth noting that previous studies have shown that alpha cells are able to replenish insulin-producing cells when beta cells are extremely absent. During this transformation, the epigenetic regulatory molecule Arx was identified as a key molecule. However, scientists have only observed this effect in living mode organisms, and it is completely unknown whether other factors of surrounding cells (even distant organs) also play a role. Pharmacist Tuna Loin,Frozen Tuna Loin,Fresh Tuna Loin,Yellowfin Tuna Loin ZHEJIANG RETRONX FOODSTUFF INDUSTRY CO.,LTD , https://www.retronxfoods.com