The new taste on CDS, needle-free injection of insulin - the two most evidence of the new technology forum for diabetes

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Release date: 2015-12-18

~ Extended reading, CDS is the English abbreviation of "Chinese Medical Association Diabetes Branch", is the country's most authoritative "diabetes" official organization. 2015CDS Suzhou Annual Meeting is the 19th National Academic Conference of the Chinese Medical Association Diabetes Association, China's top professional "diabetes" academic conference)

Each annual CDS meeting will attract medical experts from the national endocrinology field to gather and exchange the most scientific and reasonable knowledge about diabetes prevention and control. Only “foreign science”, “foreign drugs” and “foreign instruments” have always become The pillars of the conference content do not have to be detailed in the past. After all, China has not yet advanced to the forefront of the world's medical technology.


On the wall of the Huipai building below the main target board, there is a vast expanse of blue and blue. Looking at the familiar "Xiamou" can not help but want to buy a bottle of drink, stimulate the taste buds that I have already tasted. Passing the notice wall and seeing two familiar names.


The coffee in the two big coffees, I don’t know if I use Dabao every day.

Guo Lixin of Beijing Hospital & Li Qifu of Chongqing First Affiliated Hospital, one is a low-key and rigorous central health care doctor, one is a strict and low-key Chongqing Diabetes Committee, and it is a coincidence that the two big coffees are still the same Report the subject matter, I don’t know why there is no needle injection. However, Professor Guo’s topic is clear and simple. “The clinical evidence of insulin injection without needle injection to improve blood sugar control” is consistent with his consistent style. “No injection of insulin, truth or fallacy?—An empirical evidence of human clamps” is Professor Li. The title. The date is December 12, which is later than my date of returning to Beijing. Curiosity makes it happen. My Baidu "no needle injection" wants to understand what diorama is playing with "needle-free injection of insulin".

Dean Niangdao: When the drug is injected without the aid of a needle, the liquid drug directly enters the body tissue by means of ultra-fine, high-speed, straight-line high-pressure jet, thus solving a series of problems caused by the needle injection into the body. . No needle injection except the drug itself, no other foreign matter enters the body. Therefore, many authoritative sources will refer to the application of needle-free injection technology as "a revolution in medical injection technology."

Two thoughts flashed. First, what kind of needle-free injection? Second, true and false? So I went straight to the 5B exhibition area, and I was holding the 10 yuan banknotes for drinks, and I forgot the desire to drink.


Exhibitors in the B5 exhibition area without needle injection booths are as interested in the experience as I am, allowing themselves to operate. I also unexpectedly saw that CDS National Vice Chairman, Professor Shan Zhongyan is learning about needle-free injection technology. Injecting insulin, the thing of chasing the stars will be released later.

The preparation process of injection is very simple. Inhale the insulin into the tube (I use the saline instead). The upper and lower body of the needle-free syringe rotates in the opposite direction to the "click", and the injection button and the insurance button will also bounce at the same time; Turn the direction, you can see a digital display window, the scale displayed is the insulin injection dose. Let me close my eyes and trace the feelings of the time.

Hold the syringe with the tip at the disinfected injection position, press the insurance first, then press the injection button with your thumb. The sound of the syringe is obvious. The feeling of being injected is not clear in the language. It doesn't hurt very much. It seems that there is still some point. Slightly itchy and numb, but all happen in an instant, the ultimate moment to solve all concerns. You must know that I am an authoritative horror "turning home". I used to have a high fever of 39.5 degrees to go to school, just to avoid hitting the bottle. After the syringe continues to press for 10 seconds, it can be removed, looking for the location of the injection, and a vaguely marked spot marking the specific location of the saline injection. The whole operation is very convenient, the hand feels mature ergonomic design, and the injection does not need to adjust the posture or angle of the hand or body deliberately. With my poor science ability, I believe that after a maximum of 3 times, you can fully learn the full set of movements. It is. There is no picture to watch, I was really unable to take a photo at the time.

(The above text is very smooth, I was not so relaxed at the scene. I saw a few experts who tried me before I took the product boldly, and then the grass mud horse in my heart leaped and jumped until the moment the button was pressed.)

There were too many people in front of the booth, and many people gathered in front of Xiaobian to ask for feelings, in addition to constantly saying "not bad..." It seems that they have really forgotten the feeling of being just shot. At present, this product can only inject a full range of insulin, I hope that the vaccine injection that the manufacturer is applying for is approved early. The second child in the family is coming, so don't let me hold the children in line, listen to the full house crying, wait for the nurse who only shows his eyes to tie the steel needle to my apex. After I finished playing, I was full of blood and resurrected.

Forgot to say that this product is a Chinese product with completely independent intellectual property rights. After taking a single drug, the continuous injection step is the only patent in the world. The Chinese wind of the CDS begins to blow up, and it is also necessary to blow the artichokes in the field of diabetes medicine, so that the big China can show the blue sky.

CDS Annual Meeting December 12.

The second floor lecture hall, open at 8 o'clock, I arrived at 7:30, a bit late, no good location.

Professor Guo Lixin is the first big-name coffee to introduce the principle and advantages of “needle-free injection of insulin”. I will not repeat it here. It is just that Guo Daca’s magnetic baritone has always made me feel a little bit of rhythm. The conclusion of the final clinical trial of needle-free injection of insulin makes me feel that there is a stock, so I will sell it first, and I will summarize it at the end.

Professor Li Qifu’s report is still as slow as ever, but it is also rigorous and solid like a boxing fist. You should know that the blood glucose clamp test is a very accurate and authoritative test method in the test environment, and it coincides with Guo Daca's test results.
Summarize the test evidence of the two big coffees as follows:
One: no needle injection of insulin will not cause leakage and affect the complete absorption of the drug;
Two: no needle injection of insulin has the advantage of "fast onset and more stable blood sugar control" after insulin injection than traditional injection method;
Three: The patient receives insulin without needle, which is more acceptable than insulin injection.
Four: to avoid the occurrence of subcutaneous induration;
Five: For the patient, the economic burden is lighter.


Borrowing pictures of Zhang Du Niang’s encyclopedia
"Diffuse absorption" is summarized as the key point of the obvious advantage of "needle-free injection of insulin". I first made a new meaning in the field of injection and felt a new word. I recalled that after the injection on the first day, I did not press it after the injection. Subcutaneous fluid sac, although I have no evidence that subcutaneous absorption after injection is faster than needle injection, how much faster, but I can be clear that the liquid after injection is indeed scattered under the skin, which is after injection The biggest difference in needle injection. The subcutaneous absorption of the drug needs to pass through the capillaries. This is the most basic common sense. The dispersed liquid can inevitably work with more capillaries under the skin, and the damage to the subcutaneous is smaller, and it is bound to avoid long-term injection. Subcutaneous induration in insulin patients. There was also an episode after the meeting. Because there were other meetings in the back, the host had to interrupt the enthusiastic questioning doctor twice, and the doctor who asked the question directly blocked Guo Lixin at the door of the venue in order to satisfy his curiosity. Professor Guo had a 20-minute on-the-spot question at the entrance to the venue before he got out. One of the questions is very impressive.

Asked: "Professor Guo, you just mentioned that 21% of patients can't fully accept insulin without needle injection, why?"

Guo Daca: "Nokia and IPHONE6, of course, IPHONE6 is good, but you have to understand that some people insist on using Nokia, some people are not willing to change, unless there is a chance for him to feel the goodness of IPHONE"

Du Niang picture, then steal one (Guo Li two speaks no needle)

It is believed that the popularity of needle-free injection of insulin still needs a long way to go. It is also necessary for the majority of medical workers to popularize the knowledge of needle-free injection of insulin. It is faint to think that needle-free injection of insulin is just the tip of the iceberg for the application of needle-free injection technology. I don't know when I can see the whole picture, I hope it will be early.

Finally, I am allowed to say with a sense of appreciation, thanks to the scholars who have been climbing for the advancement of medical technology in China, and to the volunteers who participated in the clinical trials. You are great (especially the brothers and sisters of the blood glucose clamp, you many Drink some milk, gelatin, etc...)
CDS, next year, no needle syringe, I hope you will grow up with CDS.

“Prevention, treatment and eradication of diabetes through education, research and medical care is our mission” – CDS

Source: shawn

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