Release date: 2015-12-17 ~ 3D printers are no longer just able to make some plastic gadgets - scientists say that the 3D printed structure of filled embryonic stem cells may help doctors make the micro-organs needed for organ transplant patients in the future. Embryonic stem cells from human embryos can develop into various human cells, such as brain cells, heart cells, and bone cells. They are therefore well suited for use in regenerative medicine - repairing or replacing damaged cells, tissues, and organs. Scientists often use a variety of biological factors to induce embryonic stem cells to transform into specific tissue morphologies - a process called differentiation. At the beginning of this process, the cells form a globular mass called the embryo body, which is an active form that mimics the early stages of embryonic development. Existing research indicates that the optimal condition for embryonic stem cell growth is not a flat petri dish, but a 3D environment that mimics the human body. Recently, scientists have developed an embryonic stem cell 3D printer. The 3D printer deposits a layer of material, just like a normal printer inkjet, except that it can stack another layer of material on one layer of material to build a 3D object. In the past, embryonic stem cell 3D printers only produced flat or simple stacks, which were called cell "stalactites." Today, researchers claim that they have developed a method for printing 3D structures for the first time to fill embryonic stem cells. Co-founder Wei Sun is currently a professor of mechanical engineering at Tsinghua University in Beijing and Drexel University in Philadelphia. He told LiveScience: "We can use 3D printing technology to make embryo bodies under controlled conditions. Produce identical embryonic stem cell modules." Sun added: "In theory, these modules can be used to build tissue and even micro-organs like Lego bricks." In the experiment, the researchers also printed mouse embryonic stem cells with a hydrogel, which is similar to the materials of soft contact lenses. Because embryonic stem cells are fragile, scientists must be able to protect them—for example, finding the optimum temperature and increasing the print nozzle. According to the latest research, 90% of cells can survive the printing process. Researchers say these cells will proliferate into embryoid bodies in hydrogel scaffolds and secrete proteins that are secreted by healthy embryonic stem cells. Scientists can also dissolve the hydrogel to obtain the embryo body. The size and monodispersity of the embryo body strongly influence the type of cells that will become. Researchers say their new technology can better control the size and monodispersity of the embryo body compared to the prior art. Sun said in a statement: "The prepared embryo is very pure and can be a very good starting point for tissue growth. It is very exciting to produce embryos under controlled conditions." Rui Yao, an associate professor at Tsinghua University in Beijing, and the collaborator of the research, said: "Our next step is to study how to adjust the size of the embryo body by changing the printing and structural parameters, and how to make different by changing the size of the embryo body. Kind of cells." In the long run, researchers want to print different kinds of embryo bodies at the same time. Yao said: "This will promote the simultaneous growth of different cells in the vicinity, laying the foundation for the growth of micro-organs in the laboratory." Source: China Digital Science and Technology Museum Food additives are substances added to food to preserve flavor or enhance taste, appearance, or other sensory qualities. AMULYN can provide many different kinds of food additives, including Natural Pigment, natural sweeteners, probiotic powders, etc. Among them, the most popular one is phycocyanin, which can be used in ice cream, cocktails, and baking to add color; Lutein can be used to protect eyesight and is mainly used in health products, such as capsules and oral liquids; probiotics are mainly used to regulate the balance of intestinal microorganisms and can be used in solid beverages, yogurt, etc. Natural Pigment,Phycocyanin,Blue Spirulina Powder,Lutein,Probiotics Powder Xi'an Gawen Biotechnology Co., Ltd , https://www.amulyn-bio.com
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