PLoS Comput Biol & Sci Rep: A new tool or help with supergenome analysis

<

Release date: 2015-12-18

~

On December 17, 2015, scientists from the Icahn Sinai School of Medicine recently released a new data analysis software that will help genomics researchers identify genetic diseases with greater efficiency and accuracy. factor. These findings were published yesterday in the journals PLoS Computational Biology and Scientific Reports.

The gene expression data of the MEGENA (multi-scale embedded gene co-expression network analysis) project is applied to a three-dimensional sphere, which helps scientists study diseases characterized by complex network hierarchical patterns such as cancer, obesity, Alzheimer's disease. . Test data from the Cancer Genome Atlas (TCGA), MEGENA identified new regulatory targets in breast and lung cancer, superior to other co-expression analysis methods.

The second tool, SuperExactTest, established the first theoretical framework to assess the statistical significance of multiple sets of intersections and prompted users to compare very large data sets, such as genes from genome-wide association studies (GWAS) and differential expression analysis. set. Scientists used SuperExactTest to test TCGA and GWAS data to identify a core set of cancer genes and detect patterns between complex diseases. Both tools are from the Multiscale Network Modeling Laboratory, led by zhangbin, an associate professor of genetics and genomics.

“These tools fill the genomics of important and unmet needs,” Dr. Zhang said. “MEGENA will help scientists understand novel pathways and key goals in complex diseases, and SuperExactTest will provide a clearer genomic map by comparing a large number of gene signatures.”

“Our research team is dedicated to producing high-performance analytical tools and sharing a wide range of genomics resources to help all of us produce the best results,” said Dr. Eric Schadt. “These new tools showcase thoughtful and creative solutions to help the challenges of scientists around the world.”

Source: Bio Valley

Sampling Swab

Very high sample collection and release volumes.Greatly improved the accuracy of the inspection . Patented polymer synthetics handle 4.The hidden danger of nasopharyngeal swab rupture is completely solved.iCleano swab is ideal for collecting large amount of samples and rapid elution of thespecimens. It instantly release the specimen into the transport medium, which is welladopted in the field of molecular genetics, forensics, clinical laboratories sectors etc.

Sampling Swab,Sterile swab of disposable virus sampling tubes,Nasopharyngeal swab sample detection collection,Nasopharyngeal swab

Jiangsu iiLO Biotechnology Co., Ltd. , https://www.iilogene.com