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Ultrasonic extraction (also known as ultrasonic extraction) has the unique advantages of low extraction temperature, high extraction rate and short extraction time. It is used by innovative people to extract Chinese herbal medicines and various effective extracts of animals and plants. It is an alternative to traditional shearing. The process method realizes modern high-tech means of efficient, energy-saving and environmentally-friendly extraction.
2 Principle The superiority of ultrasonic extraction of Chinese herbal medicines is based on the special physical properties of ultrasonic waves. Mainly through the rapid mechanical vibration wave generated by the piezoelectric transducer to reduce the force between the target extract and the sample matrix to achieve solid-liquid extraction separation.
(1) Acceleration medium particle motion: When propagating in a continuous medium (such as water) of ultrasonic waves higher than the 20KHz sound wave frequency, according to the Huygens wave principle, the medium particle point (including the medicinal material is important and effective) will be caused on the wavefront of its propagation. The movement of the particle of the component causes the medium particle motion to obtain tremendous acceleration and kinetic energy. The acceleration of the particle is calculated to be more than two thousand times the acceleration of gravity. Since the medium particle exerts ultrasonic energy on the medicinal component of the medicinal material to obtain great acceleration and kinetic energy, it quickly escapes the medicinal substrate and is freed from the water.
(2) Cavitation: Ultrasonic waves propagate in liquid media to produce a special “cavitation effectâ€. The “cavitation effect†continuously generates numerous micro-cavities with internal pressures reaching thousands of atmospheres and continuously “blasting†to produce microscopic The powerful shock wave acts on the Chinese medicinal materials, so that the constituents of the medicinal materials are "bombardded" and the medicinal materials are continuously denuded. The medicinal ingredients that are not part of the plant structure are continuously separated. Accelerate the extraction of plant extracts.
(3) Ultrasonic vibration homogenization (Sonication): the effects of the points in the sample medium are consistent, so that the whole sample is more uniformly extracted.
In summary, the medicinal substances in Chinese herbal medicines not only obtain their own huge acceleration and kinetic energy as a medium particle under the action of ultrasonic field, but also obtain a strong external force impact through the “cavitation effectâ€, so they can be efficiently separated and fully separated. .
3 Advantages 1. High extraction efficiency: The unique physical properties of ultrasound promote the breakage or deformation of plant cell tissue, so that the extraction of active ingredients of traditional Chinese medicine is more complete, and the extraction rate is significantly improved by 50-500% compared with the traditional process;
2. Short extraction time: Ultrasound-enhanced Chinese medicine extraction usually obtains a good extraction rate of Zui in 24-40 minutes, and the extraction time is greatly shortened by more than 2/3 compared with the traditional method, and the raw material processing capacity of the medicinal materials is large;
3. Low extraction temperature: Ultrasonic extraction of Chinese herbal medicines has a good temperature of 40-60 ° C, which has a protective effect on the active ingredients in the heat-labile, easily hydrolyzed or oxidized medicinal materials, and greatly saves energy consumption;
4. Wide adaptability: Ultrasonic extraction of Chinese herbal medicines is not limited by the polarity of components and molecular weight, and is suitable for the extraction of most kinds of Chinese herbal medicines and various components;
5. The extraction of chemical liquid has less impurities, and the active ingredient is easy to be separated and purified;
6. The extraction process has low operating cost and significant comprehensive economic benefits;
7. The operation is simple and easy, and the equipment maintenance and maintenance are convenient.
Increase extraction rate by 50% - 500%
The extraction time (minutes) is shortened by 2/3 or more and the extraction temperature is 40-60 ° C to protect the active ingredients.
4 use introduction 1, can be used for biological and plant cell disruption;
2, can be used as biological and plant active ingredient extraction;
3. It can be used for low temperature extraction of active ingredients of Chinese herbal medicine;
4, can be used for BCR elemental extraction;
5, low energy state can activate bacteria;
6, high energy state can kill live bacteria;
7, can be used for DNA extraction and DNA cleavage;
8, can be used for gene introduction;
9, can be used for the treatment of raw wine;
10, can be used to break the dormancy state of plant seeds to improve the sprouting rate and early maturity;
11, can be used for two different quality solution polymerization
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Ultrasonic Chinese medicine extraction principle
Brief introduction to the simple method and mechanism for ultrasonic extraction of traditional Chinese medicines and natural medicines: adding an extraction solvent (water, ethanol or other organic solvents, etc.) to the container, pulverizing or cutting the Chinese medicinal materials into granules as needed, and placing them in the extraction solvent; The outer wall is bonded to the transducer vibrator or the vibrator is sealed in a stainless steel box and put into the container; the ultrasonic generator is turned on, the vibrator emits ultrasonic waves into the extraction solvent, and the 'cavitation effect' and mechanical effect generated by the ultrasonic wave in the extraction solvent are The cell wall of the medicinal material can be effectively broken, the active ingredient is in a free state and dissolved in the extraction solvent, and on the other hand, the molecular motion of the extraction solvent can be accelerated, so that the active ingredients in the extraction solvent and the medicinal material are in rapid contact, and are mutually dissolved and mixed.