Speaking of cancer and cancer, it is no longer the same as it was many years ago, but it is still feared by people. Successful treatment of tumors is still based on early detection and early treatment. So early detection and discovery of the tumor is the core of the first. Liquid biopsy is a method of detecting other cells or DNA that enters the bloodstream, replacing the diagnosis of the disease, such as a tumor. Recent hot liquid biopsies include: cfDNA (Circulating Cell-free DNA), CTC and exosomes. For information on CTC and exosomes, we have published two articles. For more information, please visit: Free circulating DNA (cfDNA) is present in the blood and contains double-stranded DNA fragments, most of which are short-chain, and usually at low concentrations. In healthy humans, plasma cfDNA is thought to be derived from normal hematopoietic cells. The circulating half-life of cfDNA is very short, suggesting that it requires sustained release during apoptosis. In certain physiological conditions or diseases, a considerable part of cfDNA is different from when it is healthy. Based on this result, cfDNA has been used for non-invasive diagnosis in recent years. Among pregnant women, about 10%-15% of cfDNA comes from the placental trophoblast. Now cfDNA is used to screen fetal defects in high-risk pregnant women. This is the basis of the current hot non-invasive Down's screening! In cancer patients, detection of tumors by quantitative mutations in cfDNA has been recognized by more and more people. In terms of transplantation, transplant rejection is also associated with cfDNA levels in donor transplanted organs. Figure.2 Complex components in the blood Circulating tumor DNA (ctDNA) is a type of cfDNA derived from tumor cells and belongs to a type of cfDNA. Both are inclusive and ctDNA is only a small part of cfDNA. ctDNA is derived from somatic mutations in tumor cells, unlike genetic mutations that are present in every cell in the body. Often when it comes to circulating tumor DNA, people tend to think of it as free DNA in the peripheral blood of cancer patients. In fact, although ctDNA accounts for a very large range of cfDNA fluctuations, about 0.01% to 90%, in fact, most ctDNA accounts for about 0.2% of cfDNA. How to effectively separate and extract cfDNA (ctDNA) for detection has become a problem that researchers must break through! As the world's leading developer and supplier of innovative technology and epigenetic research products, Epigentek has developed a rare free-circulating DNA isolation and extraction kit on the market: EpiQuik Circulating Cell-Free DNA Isolation Kit (Cat. No.: P-1064), helping you to be a step in the field of cancer research! The kit utilizes magnetic bead-based fractionation screening technology to separate mononuclear and dinucleosome complexes from serum/plasma samples and release DNA by digestion to extract free circulating DNA (cfDNA). *This kit requires a magnetic plate. The recommended accessory product is: Q10002-1 The superior advantages of the kit: Figure.3 Simple experimental procedure & reliable extraction Epigentek Group is the world's leading developer and supplier of innovative technology and epigenetic research products. The company has developed a comprehensive product portfolio of more than 400 patented products to provide comprehensive system solutions for epigenetic research and new drug development. As the general agent of Epigentek Group's China region, Amy Jie introduced it to China as its regional agent in China and will provide customers with complete epigenetic solutions, including analytical kits for antibodies, antibodies and related Products such as inhibitors/antagonists. At the same time, as a Chinese agent or regional agent of many international famous brands, Aimei can provide you with a series of laboratory solutions. If you are interested in the above products, please call the free customer line 400-6800-868 to contact Aimei Technology Co., Ltd. for product information and complete experimental solutions. For more information, please contact Ai Meijie Technology Co., Ltd.! Toll Free Email: Website: Rescue Boots,Search And Rescue Boots,Fire Rescue Boots,Mountain Rescue Boots joho(HK) Technology Co. , Ltd. , https://www.joho-safety.com
Product name and description Brand Item number product manual EpiQuik Circulating Cell-Free DNA Isolation Kit Epigentek P-1064 Details 
