New hydrogel can release dose according to the condition April 09, 2018 Source: Science and Technology Daily The British journal Nature Communications recently published a recent biomedical project: American scientists have successfully demonstrated a drug-eluting gel that responds to disease activity using a mouse model that can load different small molecules and Cleverly release the appropriate dose depending on the severity of the onset of the disease, or will open a new treatment plan for the future. The onset of many diseases is light and heavy, and the current drug delivery methods that maintain the same dose may not reach the optimal dosage, which may easily delay the disease or over-treatment. In view of this, Jeffrey Kapp, a researcher at Brigham and Women's Hospital in the United States, and colleagues have developed a hydrogel that responds to seizures, which can load different small molecules and release the corresponding dose according to the severity of the disease. They experiment in cells and mouse models of inflammatory arthritis, which break down when the gel comes into contact with arthritis-related enzymes. A corticosteroid for the treatment of arthritis is released, at which time a decrease in arthritis activity is observed. The cause of arthritis is very complicated, although it is not fatal, but severe cases can lead to joint disability and affect the quality of life of patients. Moreover, the condition of patients with inflammatory arthritis usually slows down for a while, and is anxious for a while, and the disease is anxious. The research team claims that responsive hydrogels are a potential effective treatment for inflammatory arthritis. But researchers are also cautious that more research is needed to optimize the composition of the gel, and it is necessary to test it on large animals with human-sized joints before considering human clinical trials. They believe that this achievement is the first step in the medical community's design of a response to active disease treatment programs. (Reporter Zhang Mengran) Feature: Industrial Gloves,Construction Gloves,Construction Work Gloves,Industrial Nitrile Gloves Jiangsu Asbao Medical Technology Co., Ltd. , https://www.iigloves.com
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