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Finds genes that determine the position of the mammalian embryo's head
Japanese researchers recently discovered two genes that determine the position of the head of a mammalian embryo during its development through animal experiments and clarified their mechanisms of action. The report said that previous studies showed that after five days of fertilization, the mouse's fertilized eggs will produce a cell called DVE, which will develop into a head. The DVE cells are initially located at the apex of the embryo and then gradually move to one side and eventually "root" to form a head at a specific location. Researchers at Osaka University in Japan have found two genes that are closely related to the movement of DVE cells. They found that the two genes inhibited the division of embryonic cells in a certain direction around DVE cells, while the division of cells in other directions proceeded as usual. In this way, the proliferating cell population pushed DVE cells toward the direction in which cell division was inhibited. Move and finally stop where you should be. These two genes also play an important role in determining the body's structure. Through in-depth exploration of its activities, it will provide clues for the study of the formation of asymmetric organs in mammals.