Melanotan 2 Injections Mt2 Peptide Melanotan II Skin Tanning Injections

<

Model NO.: 75921-69-6
Molecular Weight: 382.54
Absorbance: ≤0.30%
Specific Rotation: +39°~ +43°
17α-Isomer: ≤0.50%
Loss on Drying: ≤0.50%
Residue on Ignition: ≤0.10%
Leading Time: Within 12hours After Payment
Delivery Time: Wihtin 5working Days After Payment
Express: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: ZJY
Transport Package: Discreet Package
Specification: Yellow Liquid
Origin: China
HS Code: 2701129000
Model NO.: 75921-69-6
Molecular Weight: 382.54
Absorbance: ≤0.30%
Specific Rotation: +39°~ +43°
17α-Isomer: ≤0.50%
Loss on Drying: ≤0.50%
Residue on Ignition: ≤0.10%
Leading Time: Within 12hours After Payment
Delivery Time: Wihtin 5working Days After Payment
Express: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: ZJY
Transport Package: Discreet Package
Specification: Yellow Liquid
Origin: China
HS Code: 2701129000
Product Description:
1. 10mg Melanotan 1 (melanotan) peptide MT-I, Melanotan-1 for skin tanning
Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
 
2. Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R,MC3-5R). As an analogue of α-MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.
 

Melanotan-1 Peptide Amino Acid Sequence: 
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular formula: C78H111N21O19 
Molar Mass: 1646.845 
CAS number: 75921-69-6 
PubChem: CID 16154396 
Synonyms: Melanotan; Melanotan-1; Melanotan I; CUV1647; EPT1647; NDP-MSH; [Nle4, D-Phe7]α-MSH [Nle4, D-Phe7]-α-MSH Melanotan 
 

The Development of Melanotan 1
1.The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy.

2.However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1,which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule "Melanotan" (later Melanotan-1).Melanotan-1 Mechanism of Action - How it Works!

3.Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment).

4.The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.
 
Specification Quantity
MGF 2mg/vial*10vial/kit
PEG MGF 2mg/vial*10vial/kit
CJC-1295 with DAC 2mg/vial*10vial/kit
CJC-1295 without DAC 2mg/vial*10vial/kit
PT-141 10mg/vial*10vial/kit
MT-1(Melanotan-1) 10mg/vial*10vial/kit
MT-2(Melanotan-2) 10mg/vial*10vial/kit
GHRP-2 5mg/vial*10vial/kit
GHRP-2 10mg/vial*10vial/kit
GHRP-6  5mg/vial*10vial/kit
GHRP-6  10mg/vial*10vial/kit
Ipamorelin 2mg/vial*10vial/kit
Hexarelin 2mg/vial*10vial/kit
Sermorelin 2mg/vial*10vial/kit
Oxytocin 2mg/vial*10vial/kit
TB500 2mg/vial*10vial/kit
Pentadecapeptide BPC 157 2mg/vial*10vial/kit
Triptorelin 2mg/vial*10vial/kit
Tesamorelin 2mg/vial*10vial/kit
Gonadorelin 2mg/vial*10vial/kit
Gonadorelin 10mg/vial*10vial/kit
DSIP 2mg/vial*10vial/kit
Selank 5mg/vial*10vial/kit

Shipping /return /refund policy:
We will attempt to ship most orders within 48 hours excluding weekends or holidays.
International and EU orders  ship via Priority mail or DHL based on weight. Customer will be provided with tracking number. Shipment to countries with tropical clima will be in isolated  pack and with cooling inlets. After receiving all products must be placed into refrigeratot to +5° C.

All Items are shipped safely and in manner that ensures safe arrival. If for any reason this is not the case then please email us and we will work with you. Each case is handled individually.

We will accepts returns if it is due to damage that is our fault or manufacturers defects. The items that we sell are peptides and as such could degrade if improperly handled. As a result we are unable to resell products once they have left our warehouse. The return must be within 15 days of the time of the purchase.

Peptides on the other hand, due to their fragile nature and us being to monitor how they were handled when they were out of care, could possibly degrade. We prefer not to accept returns of peptides due to this fact.

If you are missing an item or the item you receive is damaged, then please contact us and we will sent out a replacement free of shiping cost to you.

The best way we serve our clients is to offer them the best advantages:
Money back guarantee
Highest quality guarantee
lowest price guarantee
Lab and analysis guarantee
Fresh batch guarantee
Laboratory test guarantee
Satisfaction guarantee
Fast delivery guarantee
Customer support guarantee Product Description:
1. 10mg Melanotan 1 (melanotan) peptide MT-I, Melanotan-1 for skin tanning
Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
 
2. Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R,MC3-5R). As an analogue of α-MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.
 

Melanotan-1 Peptide Amino Acid Sequence: 
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular formula: C78H111N21O19 
Molar Mass: 1646.845 
CAS number: 75921-69-6 
PubChem: CID 16154396 
Synonyms: Melanotan; Melanotan-1; Melanotan I; CUV1647; EPT1647; NDP-MSH; [Nle4, D-Phe7]α-MSH [Nle4, D-Phe7]-α-MSH Melanotan 
 

The Development of Melanotan 1
1.The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy.

2.However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1,which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule "Melanotan" (later Melanotan-1).Melanotan-1 Mechanism of Action - How it Works!

3.Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment).

4.The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.
 
Specification Quantity
MGF 2mg/vial*10vial/kit
PEG MGF 2mg/vial*10vial/kit
CJC-1295 with DAC 2mg/vial*10vial/kit
CJC-1295 without DAC 2mg/vial*10vial/kit
PT-141 10mg/vial*10vial/kit
MT-1(Melanotan-1) 10mg/vial*10vial/kit
MT-2(Melanotan-2) 10mg/vial*10vial/kit
GHRP-2 5mg/vial*10vial/kit
GHRP-2 10mg/vial*10vial/kit
GHRP-6  5mg/vial*10vial/kit
GHRP-6  10mg/vial*10vial/kit
Ipamorelin 2mg/vial*10vial/kit
Hexarelin 2mg/vial*10vial/kit
Sermorelin 2mg/vial*10vial/kit
Oxytocin 2mg/vial*10vial/kit
TB500 2mg/vial*10vial/kit
Pentadecapeptide BPC 157 2mg/vial*10vial/kit
Triptorelin 2mg/vial*10vial/kit
Tesamorelin 2mg/vial*10vial/kit
Gonadorelin 2mg/vial*10vial/kit
Gonadorelin 10mg/vial*10vial/kit
DSIP 2mg/vial*10vial/kit
Selank 5mg/vial*10vial/kit

Shipping /return /refund policy:
We will attempt to ship most orders within 48 hours excluding weekends or holidays.
International and EU orders  ship via Priority mail or DHL based on weight. Customer will be provided with tracking number. Shipment to countries with tropical clima will be in isolated  pack and with cooling inlets. After receiving all products must be placed into refrigeratot to +5° C.

All Items are shipped safely and in manner that ensures safe arrival. If for any reason this is not the case then please email us and we will work with you. Each case is handled individually.

We will accepts returns if it is due to damage that is our fault or manufacturers defects. The items that we sell are peptides and as such could degrade if improperly handled. As a result we are unable to resell products once they have left our warehouse. The return must be within 15 days of the time of the purchase.

Peptides on the other hand, due to their fragile nature and us being to monitor how they were handled when they were out of care, could possibly degrade. We prefer not to accept returns of peptides due to this fact.

If you are missing an item or the item you receive is damaged, then please contact us and we will sent out a replacement free of shiping cost to you.

The best way we serve our clients is to offer them the best advantages:
Money back guarantee
Highest quality guarantee
lowest price guarantee
Lab and analysis guarantee
Fresh batch guarantee
Laboratory test guarantee
Satisfaction guarantee
Fast delivery guarantee
Customer support guarantee

Dietary Supplement

Health Benefits,Spirulina Amazon,Spirulina Smoothie

DGSGG , http://www.nbpharmaceutical.com