USP Raw Powder Brinzolamide for Antiglaucoma CAS 138890-62-7

<

  • Model NO.: 138890-62-7
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Synonym: Birnzolamide
  • MW: 383.51
  • Appearance: White Powder
  • Standard: USP
  • Delivery Time: 5-7 Days
  • Transport Package: Discreet Package
  • Origin: China
  • Powder: Yes
  • Certification: HSE, ISO 9001
  • State: Solid
  • CAS: 138890-62-7
  • Mf: C12h21n3o5s3
  • Einecs: 1308068-626-2
  • Grade: Pharma Grade
  • Usage: Treating High Intraocular Pressure
  • Trademark: Saichuang
  • Specification: Enterprise standard
USP Raw Powder Brinzolamide For Antiglaucoma  CAS 138890-62-7


Quick Detail
Product Name
Brinzolamide
 
Synonym
Birnzolamide;Brinzolamide;2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-,1,1-dioxide, (4R)-;2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (R)-;AL 4862;Brinlolamide;(R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide;
 
CAS
138890-62-7
 
MF
C12H21N3O5S3
 
MW
383.51
 
EINECS
1308068-626-2
 
Appearance
White Powder
 
Grade
Pharma Grade
 
Melting Point
130.0 to 134.0 °C
 
Usage
It is carbonic anhydrase inhibitors suitable for treating high intraocular pressure or open-angle glaucoma.
 


Description

Brinzolamide is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Carbonic anhydrase is found primarily in erythrocytes(but also in other tissues including the eye). It exists as a number of isoenzymes, the most active of which is carbonic anhydrase II (CA-II).

Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion and thus lowers the intraocular pressure in the anterior chamber, presumably by reducing the rate of formation of
bicarbonate ions with subsequent reduction in sodium and fluid transport; this alleviates the effects of open-angle glaucoma.

Dosage

Shake uniformly before using. As a monotherapy or co-therapy, drop one drop into the conjunctival sac 2 times per day; 3 times a day may be better for some patients. When use it as a substitute of another anti-glaucoma drug. Stop using that drug first and start using brinzolamide eye drops in the next day.

Treatment with more than one drug should be separated by at least five minutes. It is generally recommended that oppress nasolacrimal duct or gently close your eyes after the medication in order to reduce systemic absorption.

 

Certificate of Analysis

TEST

SPECIFICATIONS

RESULTS

Appearance

White to yellow crystalline powder

White crystalline powder

Identification

A. Should meet the requirement

Conforms

B. Should meet the requirement

Conforms

Impurity A

≤0.5%

N.D.

Impurity B

≤0.3%

0.075%

Loss on drying

≤0.5%

0.085%

Residue on Ignition

≤0.1%

0.045%

Residual solvent

Ethanol≤0.5%

0.026%

Ethyl acetate≤0.5%

N.D.

Tetrahydrofuran≤0.072%

N.D.

Heavy Metal

≤20ppm

Conforms

Assay

98.0%~102.0% (Calculated on the dried basis)

99.66%



Advantage:

1. Rich Experiences.Our company has been dealt in the pharmaceutical manufacturing area for many years. Delivery areas of our products extend all around the world. we have got very good feedback from our customers of worldwide, we had established a long friendly relations and enjoyed a high reputation both at home and abroad.
Payment method: T/T, Western Union, Money Gram.

2. Discreet package.The package suits you best would be chosen to get through customs security smoothly or customized if you want.

3. Superior quality and Reasonable price.High quality guaranteed, once any problem is found, the goods would be reshipped for you.

4. Security Shipping.Shipping by express (FedEx,UPS,DHL,EMS) or by air. The most professional forwarder would be recommended for you.

5. We have stock.We can delivery goods promptly at the same day after confirming the payment.

6. Discounts.We will do some promotion at the specific time, we would inform you anytime if we have sorts of discount activities. We can give you some discounts if you order a large number of goods.

7. Warm after-sale service for you 24/7. Any of your question would be solved for the first time asap. Adhering to the principle of customer first conviction. we will provide the best and the most sincere services for your satisfaction.
 

Honey Syrup

Honey Syrup ,Pure Organic Honey ,Medicinal Honey ,Organic Honey

Honey Products Co., Ltd. , http://www.nbhoney.com