The use of mouse cells to cultivate artificial liver is expected to become popular in 5 years.

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Release date: 2010-06-21


According to the Hong Kong "Wen Wei Po" reported on the 15th, the Massachusetts General Hospital researchers successfully used mouse cells to cultivate artificial liver in the laboratory. Scientists hope that the study will be used in hospitals within five years to help humans cultivate the liver.

Researchers at the Massachusetts General Hospital first removed the cells from the liver of the mouse, leaving a "stent", and then implanted 200 million healthy hepatocytes into the scaffold for 4 times, 10 minutes each, for successful cultivation of artificial mice. The liver, which survived in the laboratory for 10 days, was able to break down the toxins; in addition, the researchers transplanted the artificial liver into mice and found it to function for hours. The report was published in the journal Nature Medicine.

Only one type of hepatocytes was used in the experiment, and the artificial liver cultivated can only play a small part of the normal liver function.

The researchers said that in the future, the experiment will be added to other cells needed by the liver, and the study will allow the liver to be transplanted for long-term operation so that it can eventually be transplanted into the human body.
Source: China News Network

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