GW501516 Sarm Metabolic Modulator GSK-516 Fat Loss Steroids Inhibitors Cardarine CAS 317318-70-0

Basic Info.

 

Description:

 

GW 501516 (or Cardarine) is a research chemical developed in the 1990s to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.
 
As research continued to grow, bodybuilders quickly caught on to GW 501516, calling it the ultimate endurance enhancing supplement. GW's ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance has made this product a staple in every athlete's cycle and PCT. With no harmful side effects found in the past 20 years, no wonder why GW 501516 has become a legend in the world of sports and athleticism.

Application:

 

GW501516 is a selective agonist (activator) of the PPARδ receptor. It displays high affinity (Ki = 1 nM) and potency (EC50 = 1 nM) for PPARδ with > 1000 fold selectivity over PPARα and PPARγ.

In rats, binding of GW501516 to PPARδ recruits the co activator PGC-1a. The PPARδ/coactivator complex in turn up regulates the expression of proteins involved in energy expenditure. Furthermore in rats treated with GW501516, increased fatty acid metabolism in skeletal muscle and protection against diet-induced obesity and type II diabetes was observed.

In obese rhesus monkeys, GW501516 increased high-density lipoprotein (HDL) and lowered very-low-density lipoprotein (VLDL). The mechanism by which PPARδ agonists increase HDL appears to be a result of increased expression of the cholesterol transporter ABCA1

Dosage:


 

The regular dosage of Cardarine is 10 to 20 mg per day. 10 mg a day is aimed for endurance, and the higher the dosage the greater the fat loss benefits are going to be.

Expect to experience more intense endurance and fat burning when taking 20 mgs, but you never want to take much more than that.

You can take it once a day or split the dosage (in the AM and PM). GW 501516 is best taken 30-45 minutes before a workout. You'll feel the difference the first time you take it.

GW501516 Sarm Metabolic Modulator GSK-516 Fat Loss Steroids Inhibitors Cardarine CAS 317318-70-0

Basic Info.

 

Description:

 

GW 501516 (or Cardarine) is a research chemical developed in the 1990s to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.
 
As research continued to grow, bodybuilders quickly caught on to GW 501516, calling it the ultimate endurance enhancing supplement. GW's ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance has made this product a staple in every athlete's cycle and PCT. With no harmful side effects found in the past 20 years, no wonder why GW 501516 has become a legend in the world of sports and athleticism.

Application:

 

GW501516 is a selective agonist (activator) of the PPARδ receptor. It displays high affinity (Ki = 1 nM) and potency (EC50 = 1 nM) for PPARδ with > 1000 fold selectivity over PPARα and PPARγ.

In rats, binding of GW501516 to PPARδ recruits the co activator PGC-1a. The PPARδ/coactivator complex in turn up regulates the expression of proteins involved in energy expenditure. Furthermore in rats treated with GW501516, increased fatty acid metabolism in skeletal muscle and protection against diet-induced obesity and type II diabetes was observed.

In obese rhesus monkeys, GW501516 increased high-density lipoprotein (HDL) and lowered very-low-density lipoprotein (VLDL). The mechanism by which PPARδ agonists increase HDL appears to be a result of increased expression of the cholesterol transporter ABCA1

Dosage:


 

The regular dosage of Cardarine is 10 to 20 mg per day. 10 mg a day is aimed for endurance, and the higher the dosage the greater the fat loss benefits are going to be.

Expect to experience more intense endurance and fat burning when taking 20 mgs, but you never want to take much more than that.

You can take it once a day or split the dosage (in the AM and PM). GW 501516 is best taken 30-45 minutes before a workout. You'll feel the difference the first time you take it.