Abiraterone Powder CAS: 154229-19-3 for Prostate Cancer

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Model NO.: 3000
CAS: 22204-24-6
Mf: C34h30n2o6s
MW: 594.68
Einecs: 244-837-1
Assay: 99%
Payment: T/T, Western Union and Money Gram
Delivery: Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: YIJING
Transport Package: According to Every Customers′s Requirements
Specification: SGS
Origin: Sh
HS Code: 1515110000
Model NO.: 3000
CAS: 22204-24-6
Mf: C34h30n2o6s
MW: 594.68
Einecs: 244-837-1
Assay: 99%
Payment: T/T, Western Union and Money Gram
Delivery: Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: YIJING
Transport Package: According to Every Customers′s Requirements
Specification: SGS
Origin: Sh
HS Code: 1515110000

Description                                           

Product Name:Abiraterone

CAS No .154229-19-3

Formula:C24H31NO 

Molecular Weight:1202.84 

CAS No.154229-19-3

Density:1.016 g/cm3

Melting Point:148-151°C

Boiling Point:1293.8 °Cat 760 mmHg

Flash Point:736.3 °C

Solubility:ethanol: 30 mg/mL

Appearance:White Powder

Introduction                                          

Abiraterone (CB-7598, CB7598, CB 7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM. Abiraterone is used in treatment of prostate cancer.

Abiraterone is the active metabolite of abiraterone acetate, which is an orally active acetate ester of the steroidal compound abiraterone with antiandrogen activity. Abiraterone acetate was approved by the U.S. Food and Drug Administration (FDA) in April 2011. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. Abiraterone is a drug used in castration-resistant prostate cancer (formerly hormone-resistant or hormone-refractory prostate cancer) -- i.e., prostate cancer not responding to androgen deprivation or treatment with antiandrogens. It is formulated as the prodrug abiraterone acetate and marketed under the trade name Zytiga.


COA                                                       

Items

Specifications

Results

Appearance

White or off-white solid

Complies

Identification

H-NMR

Complies

Melting point

223-233°C

224.3-226.2°C

Loss on drying

no more than 1.0%

0.5%

Residue on ignition

<0.2%

0.07%

Purity (HPLC)

no less than 99.0%

99.6% 

 

Packaging Details:

25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging   aluminium bag outside and double plastic bag inside                                                                          

Delivery Detail: within 3 days when get the payment 

Shipping :

We have  Professional  shipping agent, based on customers ' demand for transport

By express :FEDEX,DHL,EMS ,UPS,TNT ect.

By SEA and By Air


Abiraterone Powder CAS: 154229-19-3 for Prostate Cancer

      

Description                                           

Product Name:Abiraterone

CAS No .154229-19-3

Formula:C24H31NO 

Molecular Weight:1202.84 

CAS No.154229-19-3

Density:1.016 g/cm3

Melting Point:148-151°C

Boiling Point:1293.8 °Cat 760 mmHg

Flash Point:736.3 °C

Solubility:ethanol: 30 mg/mL

Appearance:White Powder

Introduction                                          

Abiraterone (CB-7598, CB7598, CB 7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM. Abiraterone is used in treatment of prostate cancer.

Abiraterone is the active metabolite of abiraterone acetate, which is an orally active acetate ester of the steroidal compound abiraterone with antiandrogen activity. Abiraterone acetate was approved by the U.S. Food and Drug Administration (FDA) in April 2011. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. Abiraterone is a drug used in castration-resistant prostate cancer (formerly hormone-resistant or hormone-refractory prostate cancer) -- i.e., prostate cancer not responding to androgen deprivation or treatment with antiandrogens. It is formulated as the prodrug abiraterone acetate and marketed under the trade name Zytiga.


COA                                                       

Items

Specifications

Results

Appearance

White or off-white solid

Complies

Identification

H-NMR

Complies

Melting point

223-233°C

224.3-226.2°C

Loss on drying

no more than 1.0%

0.5%

Residue on ignition

<0.2%

0.07%

Purity (HPLC)

no less than 99.0%

99.6% 

 

Packaging Details:

25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging   aluminium bag outside and double plastic bag inside                                                                          

Delivery Detail: within 3 days when get the payment 

Shipping :

We have  Professional  shipping agent, based on customers ' demand for transport

By express :FEDEX,DHL,EMS ,UPS,TNT ect.

By SEA and By Air


Abiraterone Powder CAS: 154229-19-3 for Prostate Cancer

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