Comprehensive prevention and treatment of yellow piglets and white piglets

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Yellow and white piglet, also known as newborn pig diarrhea, is a collective name for yellow piglets and white piglets, both of which are acute intestinal infectious diseases caused by the production of toxins in the intestinal tract by Escherichia coli. At present, there are numerous serotypes of isolated piglets, Astragalus membranaceus and Angelica falciparum. The effective cross-protection between the serotype vaccines is poor, which makes it difficult to control the disease. Coupled with the high incidence of yellow piglets and piglets, the mortality rate is also high, which is a major disease that seriously jeopardizes piglet production. Therefore, the comprehensive prevention and treatment of yellow piglets and white piglets is an important factor that directly affects the production efficiency of piglets.

1 Yellow piglets

Piglet jaundice is an infectious disease with dilute feces as the main symptom. It often occurs in about 1 to 3 days of age, so it is also called early-onset diarrhea. The incidence of the disease is high, and the mortality rate is also high. It occurs in many regions and pig farms in China and is one of the most important infectious diseases that endanger piglets.

1.1 Etiology The pathogen of this disease is certain pathogenic hemolytic E. coli. Common strains include: O8, O60, O115, O138, O139, O141 and other 6 strains. The bacteria secrete the enterotoxin and cause enterotoxemia, which causes the piglet to become sick or die. The occurrence of the disease is related to poor husbandry and management of sows, especially pregnant sows, such as incompetent feed, unclean shelves and so on.

1.2 Symptoms usually occur 12 to 72 hours after birth. It is often the first time a piglet develops jaundice. It quickly spreads to whole litter pigs. The disease has yellow liquid feces in the bottom row. It has a bad smell, severe anal relaxation, defecation incontinence, and feces. Water pollution tail, perineum, buttocks and hind limbs. The sick piglets are weak, often lethargic, screaming when caught, and dilute yellow feces from the anus. In the late period, the hair was rough and dull, the skin was flabby, the belly was curled up, the baby was not fed, the drinking water was plucked, the eyeballs sag, walked and wobbled, and finally the lying ground could not afford to coma and die. Some cases often do not see the diarrhea on the sudden weakness, lack of conjunctival anemia, rapid breathing, lying in the ground and soon coma and death.
1.3 The main pathological changes of the necropsy were acute catarrhal inflammation of the stomach and intestine mucosa. The intestinal changes were most severe in the duodenum, followed by the jejunum and ileum.

2 piglet white diarrhea

The clinical features of piglet whitefish are diarrhea, milky white or pale white, thick or atherosclerotic, and have a special smell of feces. Occurred in 10 to 30 days of piglets, some before and after eating piglets, it is also known as delayed diarrhea. The disease occurs throughout the year, especially in the spring and autumn and the sudden change of temperature and rainy season.

2.1 The etiological agent is pathogenic E. coli. When poor husbandry and management, such as sows over-fat, over-milk, over-nutrition of sows, unreasonable feed structure, poor milk quality, mastitis in sows, improper feed modulation of piglets, indigestion, cold in housing Humidity and sudden changes in the weather (especially a sudden drop in temperature of 3°C or more) can all induce the disease.

2.2 Symptoms The body temperature is generally normal or slightly elevated. At the beginning of the illness, she showed a lack of energy and normal or reduced milk consumption. Coarse hair. Then it squats, row milky white or gray, blood and air bubbles, sticky paste-like dilute feces, and stench. In severe cases, the feces are incontinent. The tail, anus, and its vicinity are often contaminated with excrement. The extremities are chilly and the grass is fond of nests. The skin is pale, the anemia is weak, the dehydration is thin, the skin loses its elasticity, and the action is slow and stunted. The duration varies from 2 to 3 days in short and about 1 week in length. Most people die or become chronic if they are not treated. Even if they recover, they become stiff pigs.

2.3 Changes in necropsy The pigs with short duration of disease have milk clots in the stomach, gas in the intestines, and thin chyme in the intestine. Some mucosal hyperemia, most of the mucous membranes are pale, and mesenteric lymph nodes are slightly edematous. In addition to the changes in weight loss and dehydration, the elderly in the course of the disease had empty gastrointestinal tract, or a small amount of chyme and gas. The mucosa showed a flush, the intestinal wall became thin and translucent, and the mesenteric lymph nodes edema.

3 Control

The disease should be mainly prevention, and the feeding and management of pregnant and lactating sows should be strengthened. According to the theory of Chinese Veterinary Medicine: "The infants who are breast-deficient have diseases, they must remedy their mothers, mothers and their children, and mother-in-an-an," indicating the incidence of young animals. The mother has a great relationship. Therefore, strengthening sow feeding and management, ensuring its nutritional needs during pregnancy and lactation stage, can make the fetus develop soundly, promote the sow to produce more and better milk, ensure the nutritional needs of piglets, and reduce the incidence.

3.1 Supplementing iron preparations Adding the right amount of amino acid iron in pregnant sow diets can prevent iron deficiency anemia in piglets. A large number of practices have shown that adding 50 g iron methionine per 50 kg of feed for pregnant sows can greatly reduce yellow and white piglets.

3.2 Do a good job in the regular disinfection of sheds, especially after the birth, keep the sheds hygienically and keep it cold and warm; keep the temperature between 15 and 20°C in winter as appropriate; strengthen summer ventilation and cooling, prevent heat stress, reduce heat stress, and change mats. . After farrowing, wipe the sow's breasts and nipples with 1% potassium permanganate, squeeze a few drops of milk from each nipple, and let the pigs suck the colostrum as soon as possible.

3.3 Limit diets Prenatal and postpartum 2 to 3 days to reduce the amount of sow feed to prevent excessive postpartum milk caused by piglets indigestion diarrhea, reduce the amount of feed can be fed fresh green feed.

3.4 If there are conditions for the prevention of seedling injection, one E. coli genetic engineering vaccine may be injected 20 days and 10 days before the sow's onset of labor. Without this seedling, long-acting sulfonamides or long-acting oxytetracycline can be injected intramuscularly 24 hours before sow production, which can effectively reduce the occurrence of yellow and white piglets in sows.

3.5 Supplementation of Anti-anemia Drugs Piglets are given 1 ml of blood serum per head muscle and 1 ml of sodium selenite within 3 days after birth, which can effectively improve the disease resistance of piglets. When the piglets are around the age of 10 days, deep clean loess can be collected and sprinkled in the pens to allow the pigs to eat. It also has certain preventive effects.

3.6 Intramuscular interferon Piglets 7 to 9 days after birth, in order to control concurrent or secondary infection with viral diarrhea, each piglets intramuscular injection of 30,000 U IU of interleukin in pigs has a preventive effect.

3.7 Early inducement 10 to 15 days of age began to attract food, so that the gastrointestinal tract of piglets exercise, promote gastrointestinal function, and to supplement milk nutrition, promote growth and enhance resistance.

4 treatment

Once the piglets have diarrhoea, the place where the condition is to pass the drug susceptibility test, choose sensitive drugs for treatment. Most piglets were treated with sulfamonomethoxine sodium mixed with atropine crystals and injected with gentamycin at 20,000 IU at the nest, once a day for 2 to 3 days. For milk or breast inflammation, the sow should be treated symptomatically at the same time as the piglet.

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